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US 8,906,343 B2Granted
PAA nanoplatforms containing fluorophores and targeted moieties covalently linked and photosensitizer post-loaded
AssigneesHealth Research, Inc., The Research Foundation of State University of New York, The Regents of the University of Michigan
InventorsRavindra K. Pandey, Raoul Kopelman, Anurag Gupta, Munawwar Sajjad
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Abstract
A PAA nanoparticle containing a covalently linked fluorescent dye and a post-loaded tetrapyrrolic photosensitizer.
Claims18
A composition comprising:
- PAA (polyacrylic acid) nanoparticles functionalized with amine groups and containing a tumor targeting tetrapyrrolic photosensitizer postloaded onto the PAA nanoparticles after formation of the nanoparticles and an imaging agent covalently bonded to the PAA nanoparticles and a tumor targeting moiety covalently bonded to the PAA nanoparticles.
Dependencies are inferred from the claim text.