Biological data structure having multi-lateral, multi-scalar, and multi-dimensional relationships between molecular features and other data

A computer apparatus to operate a computer system to maintain a biological data structure, the computer apparatus comprising:

• at least one non-transitory computer-readable media having computer-useable instructions embodied thereon;
• the computer-useable instructions configured to direct the computer system, when executed by the computer system, to receive data elements indicating biological molecular features and receive knowledge elements that represent biological concepts, to individually associate unique identifiers with the data elements, to maintain, for individual ones of the data elements, an internal data element set of the other unique identifiers for the other data elements and knowledge elements that are directly associated with that one individual data element, and to maintain, for the individual ones of the data elements, an external data element set of the other unique identifiers for the other data elements that have that one individual data element in their own internal data element sets, wherein the computer-useable instructions are configured to direct the computer system to:
• receive a data query indicating the molecular feature data for an individual biological entity and a search scope indicator;
• process the molecular feature data and the data elements to identify ones of the data elements having corresponding biological molecular features;
• if the search scope indicator comprises an internal and external scope, then generate a knowledge sub-graph for the individual biological entity based on both the internal data element sets and the external data element sets of the identified data elements having the corresponding biological molecular features;
• if the search scope indicator comprises an external scope, then generating the knowledge sub-graph for the individual biological entity based on the external data element sets but not the internal data element sets of the identified data elements having the corresponding biological molecular features;
• and if the search scope indicator comprises an internal scope, then generating the knowledge sub-graph for the individual biological entity based on the internal data element sets but not the external data element sets of the identified data elements having the corresponding biological molecular features.