Registering a region of interest of a body part to a landmark subsurface feature of the body part

A non-transitory computer-readable media storing a computer program that when executed by a processor of a computing device causes the computing device to perform a process, the process comprising:

• (i) receiving a medical image that includes a region of interest of a mammalian body part;
• (ii) receiving a reference image that includes a landmark subsurface feature of the mammalian body part, the landmark subsurface feature having a spatial relationship to the region of interest;
• (iii) extracting the landmark subsurface feature from the reference image;
• (iv) registering the spatial relationship between the region of interest and the landmark subsurface feature of the mammalian body part;
• and
• (v) storing in the computer-readable media or in an another computer-readable media operably coupled with the processor informational data corresponding to the registration of the spatial relationship between the region of interest and the landmark subsurface feature of the mammalian body part.

A method comprising:

• receiving a medical image and a reference image on a receiver circuit, the medical image including a region of interest of a mammalian body part, and the reference image including a landmark subsurface feature of the mammalian body part, the landmark subsurface feature having a spatial relationship to the region of interest;
• extracting the landmark subsurface feature from the reference image;
• registering the spatial relationship between the region of interest of the mammalian body part and the landmark subsurface feature of the mammalian body part;
• and
• storing in a computer-readable media informational data corresponding to the spatial relationship between the region of interest and the landmark subsurface feature of the mammalian body part.