Mass spectrometer with beam expander
AssigneeMicromass UK Limited
InventorsJeffery Mark Brown, Anthony James Gilbert, John Brian Hoyes, David J. Langridge, Jason Lee Wildgoose
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Abstract
A mass spectrometer is disclosed comprising a RF confinement device, a beam expander and a Time of Flight mass analyzer. The beam expander is arranged to expand an ion beam emerging from the RF confinement device so that the ion beam is expanded to a diameter of at least 3 mm in the orthogonal acceleration extraction region of the Time of Flight mass analyzer.
Claims18
A mass spectrometer comprising:
- a first vacuum chamber;
- a second vacuum chamber;
- an RF ion confinement device located in the first vacuum chamber;
- a Time of Flight mass analyzer arranged in the second vacuum chamber and downstream of said RF ion confinement device, said Time of Flight mass analyzer comprising an orthogonal acceleration extraction region;
- an ion beam expander including a first Einzel lens arranged in said first vacuum chamber and a second Einzel lens arranged in said second vacuum chamber, said ion beam expander being arranged downstream of said RF ion confinement device, said ion beam expander being arranged and adapted to expand an ion beam which emerges, in use, from said RF ion confinement device so that said ion beam has a diameter or a cross-sectional width>3 mm in said orthogonal acceleration extraction region.
A method of mass spectrometry conducted with a mass spectrometer including a first vacuum chamber, a second vacuum chamber, an ion beam expander having a first Einzel lens arranged in said first vacuum chamber and a second Einzel lens arranged in said second vacuum chamber,
- an RF ion confinement device and a Time of Flight mass analyzer arranged downstream of said RF ion confinement device, said Time of Flight mass analyzer comprising an orthogonal acceleration extraction region, said method comprising:
- expanding an ion beam which emerges from said RF ion confinement device with the ion beam expander so that said ion beam has a diameter or a cross-sectional width>3 mm in said orthogonal acceleration extraction region.
A mass spectrometer comprising:
- a first vacuum chamber;
- a second vacuum chamber;
- a Time of Flight mass analyzer comprising an orthogonal acceleration extraction region;
- said mass spectrometer further comprises an ion beam expander including a first Einzel lens arranged in said first vacuum chamber and a second Einzel lens arranged in said second vacuum chamber, said ion beam expander being arranged and adapted to expand an ion beam so that said ion beam has a diameter or a cross-sectional width>3 mm, >4 mm, >5 mm, >6 mm, >7 mm, >8 mm, >9 mm or >10 mm in said orthogonal acceleration extraction region.
A method of mass spectrometry conducted with a mass spectrometer including a first vacuum chamber, a second vacuum chamber, an ion beam expander having a first Einzel lens arranged in said first vacuum chamber and a second Einzel lens arranged in said second vacuum chamber, and
- a Time of Flight mass analyzer comprising an orthogonal acceleration extraction region, said method comprising:
- expanding an ion beam with the ion beam expander so that said ion beam has a diameter or a cross-sectional width>3 mm, >4 mm, >5 mm, >6 mm, >7 mm, >8 mm, >9 mm or >10 mm in said orthogonal acceleration extraction region.
A mass spectrometer comprising:
- a first vacuum chamber;
- a second vacuum chamber;
- a device including a first Einzel lens arranged in said first vacuum chamber and a second Einzel lens arranged in said second vacuum chamber, said device being arranged upstream of a Time of Flight mass analyzer, said device being arranged and adapted to reduce the turnaround time of ions orthogonally accelerated into said Time of Flight mass analyzer.
A method of mass spectrometry conducted with a mass spectrometer including a first vacuum chamber, a second vacuum chamber, an ion beam expander having a first Einzel lens arranged in said first vacuum chamber and a second Einzel lens arranged in said second vacuum chamber, said method comprising:
- reducing the turnaround time of ions prior to orthogonally accelerating said ions into a Time of Flight mass analyzer.
Dependencies are inferred from the claim text.