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US 8,895,610 B1Granted
Platinum (IV) compounds targeting zinc finger domains
OwnerHeldi Kayinventor
Life of this patent
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Abstract
This application pertains to compositions and use of platinum(IV) compounds to alter zinc-binding sites, zinc-binding domains, zinc metalloproteins or zinc-associated proteins. Such interactions alter specific activities of these zinc-binding sites and associated protein functions, therefore offering therapeutic value.
Claims2
A method of treating an infection of a viral pathogen in a subject, the method comprising:
- administering a platinum (IV) complex effective for treating an infection of a viral pathogen to the subject, the platinum IV complex comprising the structure shown in at
- least one of formula (II) or (IV):
- wherein:
- X and Y are Cl, R1 is —NO2, R2 is Cl, and R3 is —NH3;
- and
- wherein the viral pathogen has one or more zinc-binding domains associated therewith.
3 more elements
Dependencies are inferred from the claim text.