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US 8,895,579 B2Granted
Heterotricyclic AMPA receptor antagonists for treatment of epilepsy, pain, and other neurological disorders and diseases
AssigneeNorthwestern University
InventorsGeoffrey T. Swanson, Martin B. Gill, Ryuichi Sakai, Masato Oikawa
Life of this patent
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Abstract
Disclosed are heterotricyclic compounds, pharmaceutical compositions, methods of treatment, and methods for selectively antagonizing a glutamate receptor. The pharmaceutical compositions may include and the methods may utilize heterotricyclic compounds that are glutamate analogues which have specificity for AMPA receptors. The pharmaceutical compositions may be utilized to treat or prevent neurological diseases or disorders.
Claims4
A pharmaceutical composition comprising:
- (a) a compound having a formula:
- or a salt or solvate thereof;
- and
- (b) one or more pharmaceutically acceptable carriers, diluents, or excipients.
1 more element
Dependencies are inferred from the claim text.