Biguanide derivative compound
AssigneeNihon University
InventorsMuneharu Miyake, Tadashi Kusama, Takashi Masuko
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Abstract
Provided is a novel compound which simultaneously inhibits both NMDA receptors and ASIC1a, which are associated with neurodegenerative disease and so on, and thus is useful for the prevention and treatment of various nervous system diseases. A biguanide derivative represented by the following general formula (1), a salt thereof, or a hydrate of the derivative or the salt: wherein, X1 represents a halogen atom, R1 represents an alkyl group, an optionally substituted aryl group, or an optionally substituted aralkyl group.
Claims4
A compound, wherein the compound is a biguanide derivative of formula (I), a pharmaceutically acceptable salt thereof, or a hydrate of the derivative or the salt:
- wherein,
- X1 is a halogen atom, and
- R1 is an alkyl group, an optionally substituted aryl group, or an optionally substituted aralkyl group.
Dependencies are inferred from the claim text.