Compounds and methods for treating candidiasis and aspergillus infections
AssigneesCellceutix Corporation, Rutgers, The State University of New Jersey
InventorsRichard W. Scott, Katie Freeman, Haizhong Tang, Gill Diamond
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Abstract
The present disclosure provides compounds, or pharmaceutically acceptable salts thereof, for killing or inhibiting the growth of a Candida or Aspergillus species or preventing or treating a mammal having candidiasis (oral and/or disseminated) or an Aspergillus infection.
Claims4
A method of killing or inhibiting the growth of a Candida or Aspergillus species or preventing or treating a mammal having oral or disseminated candidiasis or an aspergillus infection comprising contacting the Candida or Aspergillus species with or administering to the mammal in need thereof an effective amount of a compound of Formula IV:
- wherein:
- R1 and R2 are, independently, —C(═NH)NH2, —(CH2)nNH2, or —(CH2)nNC(═NH)NH2, where n is 2, 3, or 4;
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.