Compounds and method for treatment of cancer

A method for treating a cancer in a human, comprising administering to the human a therapeutically effective amount of a compound of Formula II:

• a pharmaceutically-acceptable salt, tautomer, optical isomer, E-isomer, Z-isomer, and/or combination thereof;
• wherein:
• X is selected from S or O;
• R, R3 and R4 are each independently selected from H, halo, hydroxyl, amino, a substituted or unsubstituted hydrocarbon group, a substituted or unsubstituted heterogeneous group, a substituted or unsubstituted carbocyclic group, a substituted or unsubstituted heterocyclic group, a substituted or unsubstituted aromatic group, or a substituted or unsubstituted heteroaromatic group;
• and
• R6 to R8 are each independently selected from H, halo, hydroxyl, amino, nitro, a substituted or unsubstituted hydrocarbon group, a substituted or unsubstituted heterogeneous group, a substituted or unsubstituted carbocyclic group, a substituted or unsubstituted heterocyclic group, a substituted or unsubstituted aromatic group, or a substituted or unsubstituted heteroaromatic group, wherein the cancer is large cell lung cancer, small cell lung cancer or non-small cell lung cancer.