Pregnancy hormone combination for treatment of autoimmune diseases
AssigneeThe Regents of the University of California
InventorRhonda R. Voskuhl
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Abstract
The present invention relates to pregnancy hormone combinations and methods of treatment for autoimmune diseases having at least two hormonal components, a pregnancy hormone (such as estriol), and a gestagen (such as levonorgestrel or norethindrone) thereby providing for the continuous, uninterrupted administration of pregnancy hormones for the treatment for autoimmune disorders, such as multiple sclerosis.
Claims33
A method for treating at least one sign or symptom of multiple sclerosis, comprising administering to a subject, for a continuous administration period, a gestagen and estriol.
A method for preventing at least one sign or symptom of multiple sclerosis, comprising administering to a subject, for a continuous administration period, a gestagen and estriol.
A method for treating at least one sign or symptom of multiple sclerosis, comprising administering to a subject for a continuous administration period an effective amount of a gestagen and estriol.
A method of delaying the onset of at least one sign or symptom of multiple sclerosis, comprising administering estriol for a period of approximately 6 months, and thereafter administering a combination of estriol and a gestagen.
A method of delaying the onset of at least one sign or symptom of multiple sclerosis comprising administering estriol and interferon-β 1a for a period of about 6 months, and thereafter administering a combination of estriol, interferon-β 1a and a gestagen.
A method of delaying the onset of at least one sign or symptom of multiple sclerosis comprising administering estriol and interferon-β 1b for a period of about 6 months, and thereafter administering a combination of estriol, interferon-β 1b and a gestagen.
A method of treating at least one sign or symptom of multiple sclerosis, comprising administering estriol for a period of approximately 6 months, and thereafter administering a combination of estriol and a gestagen.
A method of treating at least one sign or symptom of multiple sclerosis comprising administering estriol and interferon-β 1a for a period of about 6 months, and thereafter administering a combination of estriol, interferon-β 1a and a gestagen.
A method of treating at least one sign or symptom of multiple sclerosis comprising administering estriol and interferon-β 1b for a period of about 6 months, and thereafter administering a combination of estriol, interferon-β 1b and a gestagen.
Dependencies are inferred from the claim text.