Back to results
US 8,895,518 B2Granted
Cooperative conveyance of basic active principles by amphiphilic acid molecules
AssigneesCentre National De La Recherche Scientifique, Universite Paul Sabatier Toulouse III
InventorsCécile Bize, Muriel Blanzat, Emile Perez, Isabelle Rico-Lattes
Life of this patent
Estimating the term…
Abstract
The present invention relates to an intermolecular association complex of an amphiphilic carrier and an active principle G, having the following general formula (I), as well as to the compositions containing same, to the uses thereof, particularly as a drug, and to the method for preparing same.
Claims19
An intermolecular association complex of an amphiphilic transporter and an active principle of the following general formula (I):
- wherein:
- S represents a carbohydrate fragment,
- R represents a hydrogen atom, a C1-C20, saturated or unsaturated, linear, branched, cyclic or aromatic hydrocarbon chain, optionally substituted by one or more fluorine atoms,
- X represents a C4-C9 alkyl, a C4-C9 alkenyl or a C4 -C9 alkynyl chain,
- Y− represents a carboxylate (—CO2−), sulfate (—O—SO3−), sulfonate (—SO3−), phosphate (—O—P(O)(ORa)O−), phosphonate (—O—P(O)RbO−) or phosphinate (—P(O)RbO−) group, with Ra representing a C1-C6 alkyl group and Rb representing a hydrogen atom or a C1-C6 alkyl group, and
- G represents an active principle comprising at least one primary, secondary or tertiary amine or guanidine functional group.
3 more elements
Dependencies are inferred from the claim text.