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US 8,895,510 B2Granted
Pan-selectin inhibitor with enhanced pharmacokinetic activity
AssigneeGlycoMimetics, Inc.
InventorJohn L. Magnani
Life of this patent
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Abstract
Compounds, compositions and methods are provided for treatment of diseases or complications associated therewith, in which a selectin plays a role. More specifically, particular glycomimetics and uses thereof are described. For example, use of particular glycomimetics for treating sickle cell disease or a cancer involving a selectin, or complications associated with either, is described.
Claims13
A compound having the formula:
- wherein
- Bz=benzoyl;
- L=linker group;
- p=0-1;
- and
- R1 is selected from:
- wherein each Q is independently selected from H and a physiologically acceptable salt.
4 more elements
Dependencies are inferred from the claim text.