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US 8,895,270 B2Granted
Method for producing β-Phenylalanine
AssigneeMitsui Chemicals, Inc.
InventorTomonori Hidesaki
Life of this patent
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Abstract
Disclosed is a method for producing a β-amino acid comprising a step of synthesizing a β-amino acid from an α-amino acid in the presence of an amino acid aminomutase. In this method, a β-amino acid is precipitated as a solid in the reaction solution.
Claims6
A method for producing (S)-β-phenylalanine from L-phenylalanine comprising:
- providing a reaction solution comprising an (S)-selective phenylalanine aminomutase, wherein said (S)-selective phenylalanine aminomutase synthesizes (S)-β-phenylalanine from L-phenylalanine;
- synthesizing (S)-β-phenylalanine beyond a saturation concentration or supersaturation concentration in said reaction solution, wherein said (S)-β-phenylalanine is precipitated out of the reaction solution as a solid;
- and
- collecting said solid (S)-β-phenylalanine from said reaction solution.
1 more element
A method for producing (R)-β-phenylalanine from L-phenylalanine comprising:
- providing a reaction solution comprising L-phenylalanine and an (R)-selective phenylalanine aminomutase, wherein said (R)-selective phenylalanine aminomutase synthesizes (R)-β-phenylalanine from L-phenylalanine;
- synthesizing (R)-β-phenylalanine beyond a saturation concentration or supersaturation concentration in said reaction solution, wherein said (R)-β-phenylalanine is precipitated out of the reaction solution as a solid;
- and
- collecting said solid (R)-β-phenylalanine from said reaction solution.
1 more element
Dependencies are inferred from the claim text.