Method for detecting human BPLP protein or a maturation product thereof
AssigneeInstitut Pasteur
InventorsCatherine Rougeot, Jean-Francois Huaulme, Marie-Noelle Ungeheuer, Anne Wisner, Evelyne Dufour
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Abstract
The invention relates to an in vitro method for prognosis, diagnosis or determination of the evolution of a condition involving an altered production of Basic Proline-rich Lacrimal Protein (BPLP) or of any of its maturation products, by detecting, or quantifying in a biological sample of a test subject, a BPLP protein or a maturation product thereof, and comparing the production of BPLP protein or maturation product with the production of the same in a biological sample of a control subject.
Claims12
A method for a detection of the presence of Basic Proline-rich Lacrimal Protein (BPLP), or of a maturation product thereof, in a biological sample comprising:
- (a) contacting a biological sample with an antibody that specifically recognizes a peptide consisting of the amino acid sequence of SEQ ID NO:3 (QRFSR);
- and
- (b) detecting the formation of a complex between the BPLP or maturation product thereof and the antibody.
Dependencies are inferred from the claim text.