Nanoparticle composition and associated methods thereof

A nanoparticle composition comprising:

• a nanoparticulate metal oxide core, wherein the metal oxide comprises a metal selected from the group consisting of iron, tantalum, zirconium, and hafnium;
• and
• a shell comprising a phosphorylated polyol comprising at least two phosphate groups, wherein at least two of the phosphate groups occupy positions in the phosphorylated polyol which constitute a 1,2 or 1,3 spatial relationship to one another and the polyol comprises a hydrophilic group selected from the group consisting of polyethylene ether moieties, polypropylene ether moieties, polybutylene ether moieties, and combinations of two or more of the foregoing hydrophilic moieties.

A nanoparticle composition, comprising:

• a nanoparticle metal oxide;
• and a phosphorylated polyol comprises one or more hydrophilic groups selected from the group consisting of polyethylene ether moieties, polypropylene ether moieties, polybutylene ether moieties, and combinations of two or more of the foregoing hydrophilic moieties, wherein the phosphorylated polyol has structure V
• wherein n is an integer from about 16 to about 150 and R1 is an alkyl group.