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US 8,895,047 B2Granted
Combined fibrinolytic and antimicrobial catheter and uses thereof
AssigneeArrow International, Inc.
InventorsNisha Gupta, Joel Rosenblatt, Daniel J. Spangler
Life of this patent
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Abstract
Implantable catheters are provided which comprise an antimicrobial agent incorporated in a coating or bulk distributed, in combination with a fibrinolytic agent incorporated in a top coating.
Claims16
An implantable catheter comprising, in combination, an antimicrobial agent that comprises chlorhexidine incorporated in a coating or bulk distributed combined with urokinase incorporated in a top coating, wherein the chlorhexidine does not decrease the fibrinolytic activity of the urokinase, and wherein the ratio of chlorhexidine/urokinase is 20/1 (weight/weight).
Dependencies are inferred from the claim text.