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US 8,895,045 B2Granted
Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof
AssigneeDePuy Mitek, LLC
InventorsDennis D. Jamiolkowski, Kelly R. Brown, Iksoo Chun, Mora Carolynne Melican
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Abstract
A biocompatible tissue implant. The tissue implant may be bioabsorbable, consists of a biocompatible polymeric foam. The tissue implant also includes a biocompatible reinforcement member. The polymeric foam and the reinforcement member are soluble in a lyophilizing solvent. The reinforcement may be annealed and/or coated.
Claims22
A method of manufacturing a biocompatible tissue implant, comprising:
- providing a solution comprising a foam forming, biocompatible polymer in a lyophilizing solvent, said solvent having a freezing point;
- providing a biocompatible polymeric reinforcement member, said reinforcement member comprising a polymer that is soluble in the lypophilizing solvent, and, a biocompatible polymeric coating having a thickness applied to said member, wherein said polymeric coating comprises a coating polymer that is substantially insoluble in the lyophilizing solvent;
- placing the polymeric reinforcement member in a cavity of a suitable mold;
- adding the solution to the cavity of the mold such that at least a part of the cavity is filled with the solution and at least part of the reinforcing member is in contact with the solution;
- and,
- cooling the reinforcement member and solution to below the freezing point of the solvent, and lyophilizing.
3 more elements
Dependencies are inferred from the claim text.