Norovirus capsid and rotavirus VP6 protein for use as combined vaccine
AssigneesTimo Vesikari, Vesna Blazevic
InventorsTimo Vesikari, Vesna Blazevic, Kirsi Nurminen, Leena Huhti, Suvi Lappalainen, Eeva Jokela
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Abstract
The present invention relates to a combined norovirus and rotavirus vaccine for prevention of norovirus and rotavirus infection and/or viral-induced diarrheal and vomiting diseases in man. More specifically, the invention comprises a method of preparing combination vaccine compositions comprising norovirus and rotavirus antigens, in particular mixtures of norovirus VLPs and rotavirus recombinant VP6 protein or double-layered VP2/VP6 VLPs. In addition, the invention relates to methods of inducing an immune response.
Claims13
An immunogenic composition comprising at least one norovirus VLP comprising a norovirus GII-4 VLP, and at least one rotavirus VP6 antigen.
Dependencies are inferred from the claim text.