Mitochondria-targeted antioxidants
AssigneesNatreon, Inc., Indian Herbs Research & Supply Company Ltd.
InventorShibnath Ghosal
Life of this patent
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Abstract
The present invention relates to a pharmaceutical or veterinary or nutritional or personal care composition comprising coenzyme Q10 (CoQ10), reduced CoQ10, or mixtures thereof and oxygenated dibenzo-α-pyrone or an amino acyl ester thereof. The composition of the present invention is able to support and/or provide therapy to individuals at risk and/or under treatment for dysfunctions of energy metabolism, and specifically, for mitochondrial diseases.
Claims6
A method of treating a mitochondrial disorder comprising administering to a subject suffering from a mitochondrial disorder a composition comprising purified (a) Coenzyme Q10 (CoQ10), reduced CoQ10, or mixtures thereof, and (b) oxygenated dibenzo-α-pyrone or an amino acyl ester thereof wherein the composition is orally administered to an adult at least 5 mg per day of the composition and 3-OS-DBP is systemically converted to 3,8(OH)2-DBP.
Dependencies are inferred from the claim text.