Methods of leukemia cell detection
AssigneeThe Regents of the University of Colorado, a body corporate
InventorsLia Gore, Deborah Deryckere, Margaret E. Macy, Natalie Serkova
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Abstract
Methods are provided for, inter alia, determining the presence of leukemia cells in a subject, determining the change or potential change in the number of leukemia cells in the subject with time, determining whether a tissue in a subject contains a plurality of leukemia cells or a plurality progenitor leukemia cells, and determining whether a leukemia therapy administered to a subject is capable of decreasing the number of leukemia cells in a tissue of the subject.
Claims10
A method of detecting a plurality of endogenous biomolecules in a tissue of a subject that has or is suspected of having leukemia, said method comprising:
- detecting an elevated level of said plurality of endogenous biomolecules relative to a standard control using a magnetic resonance apparatus, wherein said plurality of endogenous molecules comprises monounsaturated fatty acids, total lipids and an additional endogenous biomolecule selected from the group consisting of phosphatidylinositol, phosphocholine and lactate, wherein a statistically elevated level of said plurality of endogenous biomolecules is indicative of said subject having leukemia.
A method of detecting a plurality of endogenous biomolecules in a tissue of a subject undergoing leukemia therapy, said method comprising:
- detecting an elevated level of said plurality of endogenous biomolecules relative to a standard control using a magnetic resonance apparatus, wherein said plurality of endogenous molecules comprises monounsaturated fatty acids, total lipids and an additional endogenous biomolecule selected from the group consisting of phosphatidylinositol, phosphocholine and lactate, wherein a statistically elevated level of said plurality of endogenous biomolecules is indicative of said subject having leukemia.
Dependencies are inferred from the claim text.