Compositions emitting positrons and containing inorganic particles, and use thereof in medicine, especially for diagnostic processes

Abstract

The invention relates to pharmaceutical agents containing a particulate inorganic matrix having a diameter of from 0.1 nm to 100 μm, preferably 1 nm to 10 μm, particularly preferably 1 nm to 1 μm, such as, for example, topaz, (Al2F2)[SiO4], and chiolite, Na[Al3F4], preferably wavellite, Al3(PO4)2(OH,F)2, calcium carbonate, CaCO3, maghemite, γ-Fe2O3, particularly preferably zeolites, gen. formula Mn[(AlO2)x(SiO2)y] (M=metal, e.g. Na), magnetite, Fe3O4, and barium sulphate, BaSO4, and very particularly preferably gallium phosphate, GaPO4, apatite or fluorohydroxyapatite, Ca5(PO4)3(OH,F)=3Ca3(PO4)2*Ca(OH,F)2, and fluorspar, CaF2, which, in addition to the natural isotope distribution of the structure type-forming elements of the anions and cations, also contain medically usable contents of positron-emitting nuclides, such as, for example, [15]O, [30]P, [13]N, preferably [65]Ga, [11]C, particularly preferably [13]Ba, [26]Al, and very particularly preferably [68]Ga and [18]F, the preparation thereof, and the use of these composition in medicine, particularly preferably in diagnostic imaging, in particular positron emission tomography (PET), on animals and humans, and in vitro diagnostics.

Dependencies are inferred from the claim text.