Ocular delivery systems and methods
AssigneeSight Sciences, Inc.
InventorsDavid Y. Badawi, Daniel O'Keeffe, Paul Badawi
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Abstract
Described here are systems and methods for accessing Schlemm's canal and for delivering an ocular device or fluid composition therein. The ocular devices may maintain the patency of Schlemm's canal without substantially interfering with transmural fluid flow across the canal. The fluid composition may be a viscoelastic fluid that is delivered into the canal to facilitate drainage of aqueous humor by disrupting the canal and surrounding trabeculocanalicular tissues. Tools for disrupting these tissues and minimally invasive methods for treating medical conditions associated with elevated intraocular pressure, including glaucoma, are also described.
Claims16
An implant-free, ab-interno method for treating conditions of the eye comprising:
- advancing a cannula at least partially through the anterior chamber of the eye and into Schlemm's canal;
- advancing a slidable cutting tool comprising a flexible polymer from the cannula into and along a length of the canal, the slidable cutting tool having an outer diameter between about 100 and about 500 microns;
- and disrupting the trabeculocanalicular tissues using the slidable cutting tool, and not an implant, to reduce intraocular pressure.
Dependencies are inferred from the claim text.