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US 8,884,022 B2Granted
Inhibition of bacterial biofilms with aryl carbamates
AssigneeNorth Carolina State University
InventorsChristian Melander, Steven A. Rogers
Life of this patent
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Abstract
Disclosure is provided for carbamate compounds that prevent, remove and/or inhibit the formation of biofilms, compositions including these compounds, devices including these compounds, and methods of using the same.
Claims9
A compound of Formula (I)(b):
- wherein:
- R1 is an amine-substituted aryl, or R1 is a heteroaryl selected from the group consisting of:
- indazolyl, indolizinyl, isoindolyl, isoquinolyl, isothiazolyl, naphthyridinyl, phthalazinyl, purinyl, pyrazinyl, pyridazinyl, 2-pyridinyl, 3-pyridinyl, 4-pyridinyl, pyrimidinyl, pyrrolyl, quinolyl, quinoxalinyl and triazolyl;
- n=2 to 10, saturated or unsaturated;
- each occurrence of Rx and Ry is present or absent (depending upon chain saturation), and is each independently H or alkyl;
- and
- R2 is selected from the group consisting of:
- H, alkyl, alkenyl and alkynyl,
- or a pharmaceutically acceptable salt thereof.
6 more elements
Dependencies are inferred from the claim text.