Modular bioresorbable or biomedical, biologically active supramolecular materials

A supramolecular material comprising:

• (a) a polymer comprising at least two 4H-units;
• and
• (b) a biologically active compound covalently bonded to one to ten 4H-units that are not the 4H-units of (a);
• wherein the supramolecular material comprises 50.00-99.99 percent by weight of the polymer and 0.01-50.00 percent by weight of the biologically active compound, based on the total weight of the supramolecular material;
• and
• wherein the 4H-units of (a) and (b) have the general formula (3) or formula (4) and tautomers thereof:
• wherein X is nitrogen atom or a carbon atom bearing a substituent R8 selected from the group consisting of:
• (i) hydrogen;
• (ii) C1-C20 alkyl;
• (iii) C6-C12 aryl;
• (iv) C7-C12 alkaryl;
• (v) C7-C12 alkylaryl;
• (vi) polyester groups having the formula (5)
• wherein R4 and Y are independently selected from the group consisting of hydrogen and C1-C6 linear or branched alkyl, n is 1 to 6, and m is 10 to 100;
• (vii) C1-C10 alkyl groups substituted with 1-4 ureido groups according to the formula (6)
• R5—NH—C(O)—NH— (6)
• wherein R5 is selected from the group consisting of hydrogen and C1-C6 linear or branched alkyl;
• and
• (viii) polyether groups having the formula (7)
• wherein R6, Wand Y are independently selected from the group consisting of hydrogen and C1-C6 linear or branched alkyl and o is 10 to 100,
• wherein the least two 4H-units of (a) are bonded to the backbone of the polymer via R1, R2 and/or R3 with the other R1, R2 and R3 groups representing, independently, a side chain according to (i)-(viii), and
• wherein the 4H-units of (b) are bonded to the biologically active compound via R1, with R2 and R3 representing, independently, a side chain according to (i)-(viii).