Non-invasive device for synchronizing chest compression and ventilation parameters to residual myocardial activity during cardiopulmonary resuscitation

A method to treat a patient comprising:

• determining the patient is in a pulseless electrical activity (PEA) condition;
• during the PEA condition, sensing actual residual myocardial motion or residual pulsatile blood flow in the patient using one or more sensors for any of echocardiography, Doppler ultrasonography, plethysmography and phonocardiography,
• determining whether actual myocardial motion or residual pulsatile blood flow is occurring in the patient during the PEA condition, and
• in response to the determination that the actual myocardial motion or residual pulsatile blood flow is occurring, repeatedly applying a phasic therapy to the patient synchronized to the sensed actual myocardial motion or pulsatile blood flow, wherein the phasic therapy includes applying a compressive force to the chest of the patient during an ejection phase of the heart of the patient and ceasing the application of the compressive force during a relaxation phase of the heart.

A method to treat a patient who is suffering from pulseless electrical activity, shock or other ailment of the heart, the method comprising:

• determining the patient is in a pulseless electrical activity (PEA) condition;
• during the PEA condition, sensing residual myocardial activity to determine left ventricular pump function or blood filling or ejection using one or more sensors for any of echocardiography, Doppler ultrasonography, plethysmography and phonocardiography;
• determining whether actual myocardial motion or residual pulsatile blood flow is occurring in the patient during the PEA condition;
• characterizing at least one of a pattern, a timing, a force and a vector of the sensed left ventricular pump function, or blood filling or ejection;
• in response to the determination that the actual myocardial motion or residual pulsatile blood flow is occurring, repeatedly applying a phasic therapy to the patient, and
• synchronizing the phasic therapy with the characterized at least one of the pattern, the timing, the force and the vector of the determined left ventricular pump function or blood filling or ejection.

A method to treat a patient comprising:

• determining the patient is in a pulseless electrical activity (PEA) condition;
• during the PEA condition, sensing residual myocardial activity of a heart of the patient or residual pulsatile blood flow pumped by the heart using one or more sensors for any of echocardiography, Doppler ultrasonography, plethysmography and phonocardiography;
• determining that actual myocardial motion or residual pulsatile blood flow is occurring based on the sensing;
• in response to the determination that there is actual myocardial motion or residual pulsatile blood flow, repeatedly applying a phasic therapy to the patient in synchronization with the sensed myocardial activity;
• sensing actual cardiac output or a surrogate of actual cardiac output, and
• varying the application of the phasic therapy based on the sensed actual cardiac output or the surrogate.

A method to optimize vital heart organ blood flow in a patient having a chest and a heart comprising:

• determining the patient is in a pulseless electrical activity (PEA) condition;
• during the PEA condition, sensing at least one of actual residual blood flow, an indicator of the actual residual blood flow and a status of a vital organ of the patient and generating blood flow data from the sensing, wherein the sensing uses one or more sensors for any of echocardiography, Doppler ultrasonography, plethysmography and phonocardiography;
• based on the determination that the actual myocardial motion or residual pulsatile blood flow is occurring, repeatedly applying a compressive force to the chest of the patient in synchronization with the blood flow data, and
• adjusting further application of the compressive force based on current values of the blood flow data sensed after the repeated application of the compressive force.

A method for improving the cardiac output of a patient, the method comprising:

• determining the patient is in a pulseless electrical activity (PEA) condition;
• during the PEA condition, detecting residual myocardial mechanical activity and residual pump function using one or more sensors for any of echocardiography, Doppler ultrasonography, plethysmography and phonocardiography,
• determining that actual myocardial motion or residual pulsatile blood flow is occurring based on the sensing;
• in response to the determination that there is actual myocardial motion or residual pulsatile blood flow, repeatedly applying a compressive or a decompressive force to the chest at least during a portion of an ejection phase of the heart and ceasing application of the compressive force, or applying the decompressive force during a portion of the relaxation phase, and
• adjusting at least one of a start of the application of the compression force, a termination of the compression force and an initiation or termination of the decompressive force.