Method and system for detection of biological rhythm disorders
AssigneesThe Regents of the University of California, Topera, Inc., The United States of America as represented by the Department of Veterans Affairs
InventorsSanjiv Narayan, Ruchir Sehra
Life of this patent
Estimating the term…
Abstract
System, assembly and method are provided to facilitate reconstruction of cardiac information representing a complex rhythm disorder associated with a patient's heart to indicate a source of the heart rhythm disorder. The complex rhythm disorder can be treated by application of energy to modify the source of the rhythm disorder.
Claims67
A system to reconstruct cardiac information associated with a patient's heart to indicate a source of the complex rhythm disorder, the system comprising:
- at least one computing device configured to:
- receive cardiac information signals from a plurality of sensors spatially related with the patient's heart during the complex rhythm disorder,
- classify the cardiac information signals into high and low confidence signals, wherein the high and low confidence signals are separated by a confidence threshold, the confidence threshold associated with a predetermined percentage of beats having discernible activation onsets out of total beats associated with each of the high and low confidence signals;
- determine an activation onset associated with at least one low confidence signal within an acceptance time window, the acceptance time window associated with the low confidence signal indicating an earliest activation and a latest termination for a beat in the low confidence signal;
- order the activation onsets associated with the high and low confidence signals to indicate the source of the complex rhythm disorder;
- and
- treatment means for modifying the indicated source.
An assembly to facilitate reconstruction of cardiac information associated with a patient's heart to indicate a source of a complex rhythm disorder, the assembly comprising:
- a catheter comprising a plurality of sensors configured to provide cardiac information signals;
- and
- a computer-readable medium operatively coupled to the sensors, the computer-readable medium comprising instructions, which when executed by a computing device, cause the computing device to reconstruct cardiac information associated with a patient's heart to indicate a source of a complex rhythm disorder by:
- receiving cardiac information signals from a plurality of sensors associated spatially with the patient's heart during the complex rhythm disorder;
- classifying the cardiac information signals into high and low confidence signals, wherein the high and low confidence signals are separated by a confidence threshold, the confidence threshold associated with a predetermined percentage of beats having discernible activation onsets out of total beats associated with each of the high and low confidence signals;
- determining an activation onset associated with at least one low confidence signals within an acceptance time window, the acceptance time window associated with the low confidence signal indicating an earliest activation and a latest termination for a beat in the low confidence signal;
- ordering the activation onsets associated with the high and low confidence signals to indicate the source of the complex rhythm disorder;
- and treatment means for modifying the indicated source.
A method of reconstructing cardiac information associated with a patient's heart to indicate a source of a complex rhythm disorder, the method comprising a computing device:
- receiving cardiac information signals associated with a plurality of sensors spatially related with the patient's heart;
- classifying, by the computing device, the cardiac information signals into high and low confidence signals, wherein the high and low confidence signals are separated by a confidence threshold, the confidence threshold associated with a predetermined percentage of beats having discernible activation onsets out of total beats associated with each of the high and low confidence signals;
- determining, by the computing device, an activation onset associated with at least one low confidence signal within an acceptance time window, the acceptance time window associated with the low confidence signal indicating an earliest activation and a latest termination for a beat in the low confidence signal;
- ordering, by the computing device, the activation onsets associated with the high and low confidence signals to indicate the source of the complex rhythm disorder;
- and
- applying a treatment means to modify the indicated source.
A system to reconstruct cardiac information associated with a patient's heart to indicate a source of the complex rhythm disorder, the system comprising:
- at least one computing device configured to:
- receive cardiac information signals from a plurality of sensors spatially related with the patient's heart during the complex rhythm disorder,
- classify the cardiac information signals into high and low confidence signals, wherein the high and low confidence signals are separated by a confidence threshold, the confidence threshold associated with a predetermined percentage of beats having discernible activation onsets out of total beats associated with each of the high and low confidence signals;
- determine an activation onset associated with at least one low confidence signal within an acceptance time window, the acceptance time window associated with the low confidence signal indicating an earliest activation and a latest termination for a beat in the low confidence signal;
- order the activation onsets associated with the high and low confidence signals;
- and
- output the activation onsets associated with the high and low confidence signals as ordered to indicate the source of the complex cardiac rhythm disorder;
- and a device configured to administer treatment at the indicated source.
Dependencies are inferred from the claim text.