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US 8,865,947 B2Granted
Process for producing fluorinated alcohols
AssigneeE. I. Du Pont de Nemours and Company
InventorsKenneth Gene Moloy, Sheng Peng
Life of this patent
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Abstract
The present invention is directed to a process for preparation of fluorinated alcohols of Formula (I) RfCH2CH2OH (I) by contacting a fluorinated iodide with an alkyl vinyl ether in the presence of an initiator and a base to generate an intermediate hemi-acetal or aldehyde or a mixture thereof, followed by hydrogenation of the hemi-acetal of Formula (II) RfCH2CH(OCxH2x+1)m(OH)p (II) or aldehyde of Formula (III) RfCH2CHO (III) or a mixture thereof, to yield a compound of Formula (I).
Claims20
A process for preparation of a compound of Formula (I)
- RfCH2CH2OH (I)
- wherein
- Rf is linear or branched CnF2n+1 optionally interrupted by at least one oxygen, CH2, CH2CH2, or CH2CF2;
- and
- n is 1 to 10;
- comprising
- a) contacting a compound of formula RfI, wherein Rf is defined as above, with an alkyl vinyl ether containing 1 to 4 carbons in the alkyl, in the presence of an initiator and a base to generate a mixture of intermediates comprising an hemi-acetal of Formula (II) and an aldehyde of Formula (III)
- RfCH2CH(OCxH2x+1)m(OH)p (II)
- RfCH2CHO (III)
- wherein Rf is defined as above, m is 0 to 1;
- and p is 1 to 2;
- provided that m+p is 2;
- and x is 1 to 4;
- and
- b) hydrogenating, under acidic conditions, the mixture comprising the hemi-acetal of Formula (II) and aldehyde of Formula (III) to yield a compound of Formula (I).
12 more elements
Dependencies are inferred from the claim text.