Androgen receptor modulator compounds and methods

A method for modulating an activity of an androgen receptor comprising contacting an androgen receptor with a compound of Formula (II):

• wherein:
• R1 is NO2 or CN;
• R2 is selected from among F, Cl, Br, I, SRA, NO2, and CF3;
• R3and R4 are each independently selected from hydrogen, F, Cl, ORA, an optionally substituted C1-C4 alkyl, and CF3;
• R5 is hydrogen;
• R10 is hydrogen;
• R6a and R7a are each independently hydrogen or an optionally substituted C1-C6 alkyl;
• R9 is selected from an optionally substituted C1-C8 alkyl, C1-C8 heteroalkyl, CH(RD)ORA, CH(RD)NRARB, and CORA;
• R12 and R13 are each independently selected from hydrogen, F, Cl, ORA, and (CH2)mRC;
• RA is hydrogen;
• RB is hydrogen;
• RC is selected from an optionally substituted aryl and an optionally substituted heteroaryl that is optionally with a substituent selected from F, Cl, Br, I, CN, ORA, NO2, NRARB, SRA, SORA, SO2RA, an optionally substituted C1-C4 alkyl, CF3, and an optionally substituted C1-C4 heteroalkyl;
• RD is hydrogen or CF3;
• Z is CRARB;
• n is 0;
• and
• in is 1 or 2,
• or a pharmaceutically acceptable salt thereof.