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US 8,865,123 B1Granted
Strontium phosphate microparticle for radiological imaging and therapy
AssigneeMo-Sci Corporation
InventorsDelbert E. Day, Yiyong He
Life of this patent
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Abstract
This invention relates to strontium-phosphate microparticles that incorporate radioisotopes for radiation therapy and imaging.
Claims25
A crystalline strontium phosphate radiomicroparticle comprising:
- a crystalline strontium phosphate microparticle with at least one radioisotope suitable for radioimaging and/or radiotherapy bonded to the surface thereof,
- wherein the crystalline strontium phosphate microparticle has a surface area of between about 90 and about 200 square meters per gram.
A method of administering crystalline strontium-phosphate radiomicroparticles to a patient in need thereof, comprising:
- locally delivering the crystalline strontium phosphate radiomicroparticles in a physiologically acceptable carrier by catheter or suitable intravenous injection to a tissue target or organ of the patient,
- wherein the crystalline strontium phosphate radiomicroparticles comprise crystalline strontium phosphate microparticles with at least one radioisotope suitable for radioimaging and/or radiotherapy bonded to the surfaces thereof, and
- wherein the crystalline strontium phosphate microparticles have a surface area of between about 90 to about 200 square meters per gram.
A method of obtaining a radiologic image of a specific tissue or organ of a patient, comprising:
- administering crystalline strontium phosphate radiomicroparticles in a physiologically acceptable carrier by catheter or suitable intravenous injection to a tissue target or organ of the patient and
- obtaining the radiologic image of the specific tissue or organ of the patient by capturing the gamma radiation emitted by the radiodiagnostic agent using a suitable radionuclide imaging technique,
- wherein the crystalline strontium phosphate radiomicroparticles comprise crystalline strontium phosphate microparticles with at least one radioisotope suitable for radioimaging bonded to the surface thereof, and
- wherein the crystalline strontium phosphate microparticles have a surface area of between about 90 to about 200 square meters per gram.
1 more element
Dependencies are inferred from the claim text.