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US 8,859,956 B2Granted
Ion generation using wetted porous material
AssigneePurdue Research Foundation
InventorsZheng Ouyang, He Wang, Nicholas E. Manicke, Robert Graham Cooks, Qian Yang, Jiangjiang Liu
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Abstract
The invention generally relates to systems and methods for mass spectrometry analysis of samples. In certain embodiments, the invention provides a mass spectrometry probe including at least one porous material connected to a high voltage source, in which the porous material is discrete from a flow of solvent.
Claims24
A mass spectrometry system comprising:
- a probe comprising at least one porous material that tapers to at least one tip and that is connected to a high voltage source such that an electric field is generated at a tip of the material, wherein the porous material is discrete from a flow of solvent and the probe operates without pneumatic assistance;
- and
- a mass analyzer.
A method for analyzing a sample comprising:
- contacting a sample to a probe comprising at least one porous material that tapers to at least one tip, wherein the porous material is kept separate from a flow of solvent and the probe operates without pneumatic assistance;
- applying a high voltage to the porous material such that an electric field is generated at a tip of the material so as to generate ions of an analyte in the sample that are expelled from the porous material;
- and
- analyzing the expelled ions.
1 more element
Dependencies are inferred from the claim text.