Host cells with artificial endosymbionts
AssigneeBell Biosystems, Inc.
InventorsCaleb B. Bell, III, Alexey Bazarov
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Abstract
The present invention is directed generally to eukaryotic cells comprising single-celled organisms that are introduced into the eukaryotic cell through human intervention and which transfer to daughter cells of the eukaryotic cell through at least five cell divisions, and methods of introducing such single-celled organisms into eukaryotic cells. The invention also provides methods of using such eukaryotic cells. The invention further provides single-celled organisms that introduce a phenotype to eukaryotic cells that is maintained in daughter cells. The invention additionally provides eukaryotic cells containing magnetotactic bacteria.
Claims22
An isolated, living eukaryotic cell comprising at least one intracellular magnetotactic bacterium capable of being transferred to daughter cells of the eukaryotic cell through at least three cell divisions of the eukaryotic cell, wherein the isolated, living eukaryotic cell is a mammalian cell.
Dependencies are inferred from the claim text.