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US 8,858,946 B2Granted
Method for inhibiting HIV-1 replication utilizing anti-GBV-C E2 antibodies
AssigneesUniversity of Iowa Research Foundation, The United States of America as represented by the Secretary of the Department of Veterans Affairs
InventorsJack T. Stapleton, Jinhua Xiang, Donna Klinzman, James H. McLinden
Life of this patent
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Abstract
GB virus C (GBV-C or hepatitis G virus) is a flavivirus that frequently leads to chronic viremia in humans. The invention provides compositions and methods involving an anti-GBV-C antibody or other GBV-C binding agent, or a GBV-C antigen, for inhibiting and treating HIV infections.
Claims8
A method for inhibiting HIV-1 replication comprising providing to a subject an anti-GBV-C E2 antibody, wherein the antibody attenuates HIV-1 infectivity.
Dependencies are inferred from the claim text.