Fiber wadding for filling bone defects
AssigneesNagoya Institute of Technology, Orthorebirth Co., Ltd.
InventorsToshihiro Kasuga, Akiko Obata, Kie Fujikura, Yoshio Ota, Xianfeng Yao
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Abstract
A fiber wadding for filling bone defects having a flocculent three-dimensional structure is disclosed. The fiber wadding includes a plurality of fibers that contain a biodegradable resin as a principal component and a siloxane. Outside diameter of the plurality of fibers of the wadding is from about 0.05 μm to about 30 μm. Bulk density of the fiber wadding is about 0.005-0.3 g/cm3.
Claims11
A fiber wadding for filling bone defects having a flocculent three dimensional structure, the fiber wadding comprising biodegradable fibers produced by using an electrospinning apparatus having multiple nozzles and a charged collector filled with ethanol,
- wherein the biodegradable fibers comprise a biodegradable resin and silicon-releasable calcium carbonate micro-particles,
- wherein outside diameter of the biodegradable fibers is from about 0.05 μm to about 30 μm;
- and
- wherein a bulk density of the fiber wadding, as measured in accordance with JIS L 1097, is from about 0.01 g/cm3 to about 0.1 g/cm3.
A fiber wadding for filling bone defects, comprising biodegradable fibers produced by using an electrospinning apparatus having multiple nozzles and a charged collector filled with ethanol,
- wherein the biodegradable fibers comprise a biodegradable resin, vaterite phase calcium carbonate micro-particles, a siloxane dispersed in the micro-particles, and a calcium phosphate,
- wherein outside diameter of the biodegradable fibers is from about 0.05 μm to about 30 μm;
- and
- wherein the biodegradable fibers are entangled each other in three dimensional directions to form a flocculent three dimensional structure such that the fiber wadding has a bulk density of 0.01 g/cm3 to about 0.1 g/cm3, compressibility of about 10-55%, compression recovery of about 5-76% as measured in accordance with JIS L 1097.
Dependencies are inferred from the claim text.