Thuricin CD, an antimicrobial for specifically targeting Clostridium difficile
AssigneesUniversity College Cork, Teagasc, The Agriculture and Food Development Authority
InventorsColin Hill, Mary Rea, Paul Ross
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Abstract
The present invention relates to a new bacteriocin, to microbial strains which can produce it and to uses of the bacteriocin and the strains. The bacteriocin is effective against Clostridium difficile and Listeria monocytogenes amongst other organisms.
Claims15
A biologically pure Bacillus thuringiensis strain 6431 as deposited with the National Collection of Industrial and Marine Bacteria under the Accession No. 41490 encoding a bacteriocin effective against Clostridium difficile and Listeria monocytogenes.
A bacteriocin designated Thuricin CD effective against Listeria monocytogenes and Clostridium difficile, produced by a bacterial strain Bacillus thuringiensis strain 6431 as deposited with the National Collection of Industrial and Marine Bacteria under the Accession No. 41490 wherein the Thuricin CD comprises 2 peptides, Trn-α and Trn-β, the Trn-α having a molecular mass of about 2763 daltons and the Trn-β having a molecular mass of about 2861 daltons.
Dependencies are inferred from the claim text.