Collective chirality of binary plasmonic nanoparticles Janus assemblies
AssigneesLibing Wang, Chuanlai Xu, Liguang Xu, Xiaoling Wu
InventorsLibing Wang, Chuanlai Xu, Liguang Xu, Xiaoling Wu
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Abstract
Multiple properties of plasmonic assemblies are determined by their geometrical organization. This patent focuses on the formation of Janus structure of the asymmetric assembly structure of the gold nanorods and gold nanoparticles. Chiral structure of gold nanorods and gold nanoparticles can be obtained through the characterization of optical spectra of the Janus structure. And it opens the door for the explanation of the mechanism of the chirality, plays a strong guiding role in the negative refractive material above and has good application prospects.
Claims10
A novel preparation method of nanoparticle Janus assemblies comprising the steps of:
- (1) synthesizing gold nanoparticle (SU NPs) by reduction of HAuCl4 using trisodium citrate;
- (2) preparing gold nanorods (Au NRs) by seed-mediated growth procedure;
- (3) coupling the synthesized Au NPs with first sulfydryl modified single strand oligonucleotides of SEQ ID NO:
- 1 (DNA1) to form gold nanoparticle-DNA1 conjugate (Au NP-DNA1);
- (4) coupling the prepared Au NRs with second sulfydryl modified single strand oligonucleotides of SEQ ID NO:
- 2 (DNA2) to an outer surface of Au NR to form DNA2 conjugate (Au NR-DNA2);
- (5) conjugating magnetic nanoparticles (MNP) with third amino modified single strand oligonucleotides of SEQ ID NO:
- 3 (DNA3) by 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) procedure to form magnetic nanoparticles-DNA conjugates (MNP-DNA3), wherein the DNA2 is complementary to a first part of the DNA3;
- (6) hybridizing the prepared Au NR-DNA2 with MNP-DNA3 to form an assembly of the Au NR-DNA2 and MNP-DNA3;
- (7) after adding fourth single strand oligonucleotides of SEQ ID NO:
- 4 (DNA4) that is complementary to a second part of the DNA3 to hybridize DNA4 with DNA3 and form an assembly of Au NR-DNA2, DNA4 and MNP-DNA3, adding a DNA ligase to link the Au NR-DNA2 and the DNA4 in the assembly of Au NR-DNA2, DNA4 and MNP-DNA3;
- (8) dissociating the assembly of Au NR-DNA2, DNA4 and MNP-DNA3 formed in the step (7) at the melting temperature to free Au NR-DNA2-DNA4 from MNP-DNA3, then recovering the Au NR-DNA2-DNA4 through magnetic separation;
- (9) based on step (3) and (8), hybridizing the prepared Au NP-DNA1 with Au NR-DNA2-DNA4 to obtain binary plasmonic nanoparticles Janus assemblies;
- (10) characterizing the prepared binary nanoparticles Janus assemblies based on step (9) by transmission electron microscopy (TEM), circular dichroism spectra (CD) as well as synchotron small-angle X-ray scattering (S-SAXS).
Dependencies are inferred from the claim text.