# US 8,821,916 B2 · Medical dressing comprising an antimicrobial silver compound > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 8,821,916 B2 - Document ID: US8821916B2 - Status: Granted - Kind: B2 - Application number: 12/007,053 - Filed: 2008-01-04 - Published: 2008-06-26 - Granted: 2014-09-02 - Earliest claimed: 2001-02-08 - Assignees: Coloplast A/S - Applicants: Brian Nielsen - Inventors: Brian Nielsen - Web page: https://patentgrep.com/patent/US8821916B2 ## CPC - A61L 28/0038: {Medicaments; Biocides} - A61L 15/18: containing inorganic materials - A61L 15/44: Medicaments - A61L 15/46: Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria - A61L 26/0066: {Medicaments; Biocides} - A61L 27/14: Macromolecular materials - A61P 17/02: for treating wounds, ulcers, burns, scars, keloids, or the like - A61P 31/04: Antibacterial agents - C08L 69/00: Compositions of polycarbonates; Compositions of derivatives of polycarbonates - A61L 2300/102: Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates - A61L 2300/104: Silver, e.g. silver sulfadiazine - A61L 2300/404: Biocides, antimicrobial agents, antiseptic agents - A61L 2300/602: Type of release, e.g. controlled, sustained, slow - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) - A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS - C08L: COMPOSITIONS OF MACROMOLECULAR COMPOUNDS (compositions based on polymerisable monomers C08F, C08G; artificial filaments or fibres D01F; textile treating compositions D06) ## Abstract A medical dressing comprising a complex of silver and being capable of releasing antimicrobial silver ion activity, said complex comprising silver and a transition element of Group IV of the periodic system of elements enables a controlled release of silver ion activity to a wound bed. ## Claims ### Claim 1 A dry medical dressing comprising: a) a silver sodium hydrogen zirconium phosphate complex; b) at least one non-ionic absorbing element comprising a hydrocolloid, wherein said absorbing element is a separate element in said dressing; c) wherein said silver sodium hydrogen zirconium phosphate complex is mixed within said hydrocolloid absorbing element such that the concentration of silver ion is between about 0.01 to 30 mg silver/cm2; d) wherein said hydrocolloid absorbing element releases the silver ion from said silver sodium hydrogen zirconium phosphate complex only when said hydrocolloid absorbing element is placed in contact with wound exudate or fluid containing monovalent cations; and e) wherein said silver ion is released in an effective amount to exhibit antiseptic activity in a wound when placed in contact with a wound secreting exudate or fluid containing monovalent cations. ### Claim 2 (depends on 1) A medical dressing as claimed in claim 1, wherein said dressing comprises a polyurethane foam layer forming at least a part of the skin contacting surface of the dressing. ### Claim 3 (depends on 1) A medical dressing as claimed in claim 1, wherein the skin contacting surface comprises an area having a skin friendly adhesive. ### Claim 4 (depends on 1) A medical dressing as claimed in claim 1, wherein said dressing is in the form of a wound dressing or an ostomy appliance or a dressing for covering an incision site in the skin. ### Claim 5 (depends on 1) A method of absorbing exudate from a wound or from an artificial orifice or opening and treating the same with silver ions, which method comprises the steps of: a) identifying the wound, artificial orifice or opening of the patient; and b) securing a medical dressing comprising the dressing of claim 1 in such a manner that said dressing covers the area of a wound or surrounds the area of the artificial orifice or opening. ### Claim 6 (depends on 5) The method of absorbing exudates of claim 5, wherein said artificial orifice or opening is the end of an intestine or stoma protruding from the skin of a human body, or the skin around a stoma, or the area around an incision point for drainage. ### Claim 7 A dry medical dressing comprising: a) a silver sodium hydrogen zirconium phosphate complex; b) at least one non-ionic absorbing element comprising a hydrocolloid, wherein said absorbing element is homogenously distributed in said dressing; c) wherein said silver sodium hydrogen zirconium phosphate is mixed within said hydrocolloid absorbing element such that the concentration of silver ion is between about 0.01 to 30 mg silver/cm2; d) wherein said silver sodium hydrogen zirconium phosphate complex releases said silver ion from said silver sodium hydrogen zirconium phosphate complex only when said hydrocolloid absorbing element is placed in contact with wound exudate or fluid containing monovalent cations; and e) wherein said silver ion is released in an effective amount to exhibit antiseptic activity in a wound when placed in contact with a wound secreting exudate or fluid containing monovalent cations. ### Claim 8 (depends on 7) A medical dressing as claimed in claim 7, wherein said dressing comprises a polyurethane foam layer forming at least a part of the skin contacting surface of the dressing. ### Claim 9 (depends on 7) A medical dressing as claimed in claim 7, wherein the skin contacting surface comprises an area having a skin friendly adhesive. ### Claim 10 (depends on 7) A medical dressing as claimed in claim 7, wherein said dressing is in the form of a wound dressing or an ostomy appliance or a dressing for covering an incision site in the skin. ### Claim 11 (depends on 7) A method of absorbing exudate from a wound or from an artificial orifice or opening and treating the same with silver ions, which method comprises the steps of: a) identifying the wound, artificial orifice or opening of the patient; and b) securing a medical dressing comprising the dressing of claim 7 in such a manner that said dressing covers the area of a wound or surrounds the area of the artificial orifice or opening. ### Claim 12 (depends on 11) The method of absorbing exudates of claim 11, wherein said artificial orifice or opening is the end of an intestine or stoma protruding from the skin of a human body, or the skin around a stoma, or the area around an incision point for drainage.