Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders
AssigneeVeroScience LLC
InventorAnthony Cincotta
Life of this patent
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Abstract
The present invention is directed to a method of treating a patient suffering from the metabolic syndrome and/or related disorders including obesity, Type 2 diabetes, pre-diabetes, hypertension, dyslipidemia, insulin resistance, endothelial dysfunction, pro-inflammatory state, and pro-coagulative state, and comprising the steps of (a) providing to the patient a dietary regimen that decreases overactive CNS noradrenergic tone; followed by (b) providing to the patient a dietary regimen that increases dopaminergic tone while maintaining the above decreased overactive CNS noradrenergic tone. The present invention is also directed to food products useful in implementing the dietary regimens.
Claims11
A method of treating a patient suffering from a condition selected from the group consisting of metabolic syndrome, obesity, type 2 diabetes, pre-diabetes, hypertension, dyslipidemia, insulin resistance, endothelial dysfunction, pro-inflammatory state, and pro-coagulative state, comprising the steps of:
- (a) providing to said patient suffering from a condition selected from the group consisting of metabolic syndrome, obesity, type 2 diabetes, pre-diabetes, hypertension, dyslipidemia, insulin resistance, endothelial dysfunction, pro-inflammatory state, and pro-coagulative state a food product that decreases overactive CNS noradrenergic tone;
- wherein said food product that decreases overactive CNS noradrenergic tone comprises:
- 1) protein intake of about 25%±5% of total daily caloric intake;
- 2) monounsaturated fat intake of about 25%±5% of total daily caloric intake;
- 3) saturated fat intake of about 5%±5% of total daily caloric intake;
- 4) polyunsaturated fat intake of about 3%±5% of total daily caloric intake;
- 5) complex carbohydrate intake of about 42%±7% of total daily caloric intake;
- and
- 6) total caloric intake set at 15-25% less than the said patient's daily energy expenditure;
- followed by
- (b) providing to said patient a food product that increases dopaminergic tone while maintaining said decreased overactive CNS noradrenergic tone;
- wherein said food product that increases dopaminergic tone while maintaining said decreased overactive CNS noradrenergic tone comprises:
- 1) protein intake of about 24%±5% of total daily caloric intake;
- 2) monounsaturated fat intake of about 23%±5% of total daily caloric intake;
- 3) saturated fat intake of about 5%±5% of total daily caloric intake;
- 4) polyunsaturated fat intake of about 3%±5% of total daily caloric intake;
- 5) complex carbohydrate intake of about 45%±7% of total daily caloric intake;
- 6) total caloric intake set at 0-25% less than said patient's daily energy expenditure;
- and
- 7) L-DOPA-containing foods in an amount sufficient to ingest about 20-400 mg of L-DOPA per day;
- and
- wherein said polyunsaturated fat intake in each of steps (a) and (b) individually comprise a ratio of omega-3 to omega-6 polyunsaturated fatty acids from between about 0.25:1 to about 2:1;
- and
- wherein said providing step (a) continues for approximately 4 to 12 weeks;
- and wherein said providing step (b) continues for approximately 4 to 6 months.
Dependencies are inferred from the claim text.