Methods for intravascularly-induced neuromodulation
AssigneeMedtronic Ardian Luxembourg S.a.r.l.
InventorsDenise Zarins, Nicolas Zadno, Benjamin J. Clark, Erik Thai
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Abstract
Methods for intravascularly-induced renal neuromodulation. In some embodiments, a method can include positioning a pair of bipolar electrodes within renal vasculature of a human patient and expanding a balloon within the renal vasculature. The method can further include delivering an electric field via the bipolar electrodes.
Claims26
A method for intravascularly-induced renal neuromodulation, the method comprising:
- intravascularly positioning a catheter comprising a balloon and a pair of bipolar electrodes within renal vasculature of a human patient;
- expanding the balloon within the renal vasculature;
- and
- delivering an electric field via the bipolar electrodes to induce renal neuromodulation,
- wherein inducing renal neuromodulation results in a therapeutically beneficial reduction in blood pressure of the patient.
A method for catheter-based renal denervation of a human patient, the method comprising:
- transluminally positioning a renal denervation catheter within a renal artery of the patient and adjacent to neural fibers that innervate a kidney of the patient, wherein the catheter includes a balloon and a pair of bipolar electrodes;
- inflating the balloon within the renal artery of the patient;
- and
- after inflating the balloon, at least partially ablating the neural fibers of the patient via energy from the bipolar electrodes,
- wherein at least partially ablating the neural fibers results in a therapeutically beneficial reduction in central sympathetic overactive of the patient.
A method for treating a human patient diagnosed with hypertension, the method comprising:
- positioning a catheter comprising a balloon and a pair of electrode poles within renal vasculature of the patient;
- expanding the balloon within the renal vasculature;
- and
- thermally inhibiting neural communication along neural fibers that innervate a kidney of the patient via an electric field from the electrode poles,
- wherein inhibiting the neural communication results in a therapeutically beneficial reduction in blood pressure of the patient.
Dependencies are inferred from the claim text.