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US 8,818,501 B2Granted
Method and system for treating acute heart failure by neuromodulation
AssigneeThe Cleveland Clinic Foundation
InventorsSandra Machado, Marc Penn, Ali R. Rezai, Alex Smith
Life of this patent
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Abstract
Methods and systems of treating acute heart failure by applying a therapy signal at least one sympathetic cardiopulmonary fiber surrounding the pulmonary trunk that affects heart contractility more than heart rate. Methods and systems also include adjusting the signal to effectuate treatment.
Claims23
A method of treating acute heart failure in a patient in need thereof comprising:
- inserting a delivery device into a pulmonary artery;
- and
- applying a therapy signal to sympathetic cardiopulmonary fibers surrounding the pulmonary artery to selectively modulate the sympathetic cardiopulmonary fibers to treat the acute heart failure, wherein the sympathetic cardiopulmonary fibers affect heart contractility more than heart rate, wherein the modulation increases heart contractility.
A system for treating acute heart failure comprising:
- a delivery device configured for positioning in a pulmonary artery;
- and
- a controller in communication with the delivery device programmed to enable the delivery device to apply a therapy signal to sympathetic cardiopulmonary fibers surrounding the pulmonary artery to treat acute heart failure, wherein the sympathetic cardiopulmonary fibers affect heart contractility more than heart rate, wherein the application of the therapy signal increases heart contractility.
A method of affecting heart contractility more than heart rate in a patient comprising:
- inserting a delivery device into a pulmonary artery of the patient;
- and
- applying a therapy signal to sympathetic cardiopulmonary fibers surrounding the pulmonary artery to selectively modulate the sympathetic cardiopulmonary fibers to affect heart contractility more than heart rate, wherein the modulation increases heart contractility.
Dependencies are inferred from the claim text.