Use of Mycoplasma bovis antigen
AssigneeBoehringer Ingelheim Vetmedica GmbH
InventorsMichael Beck, Phillip Wayne Hayes, Jeffrey P. Knittel
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Abstract
The present invention relates to combination vaccines and/or the combined use of immunogenic compositions for the treatment and/or prophylaxis of cattle against microbiological infections, wherein the infections are caused by M. bovis and at least one further cattle relevant pathogen. The combination vaccine as described herein comprises at least one M. bovis antigen, preferably the attenuated, avirulent M. bovis as provided herewith and one or more further immunologically active components effective for the treatment and/or prophylaxis of infections caused by a further pathogen of cattle.
Claims15
An immunogenic composition for the treatment of cattle against microbiological infections, wherein said immunogenic composition comprises:
- a) one or more attenuated avirulent Mycoplasma bovis (M. bovis) antigens, wherein M. bovis bacterium is passaged more than 100 times, wherein the M. bovis bacterium is selected from the group consisting of:
- the attenuated M. bovis bacteria strains deposited with the ATCC under accession numbers PTA-8694, PTA-8695, or PTA-8696;
- and
- b) one or more further immunologically active component(s) effective for the treatment of microbiological infection in cattle caused by a cattle pathogen other than M. bovis.
A method of co-administration of two or more antigens to a cattle comprising, administering to said cattle one or more attenuated avirulent M. bovis antigen, wherein the M. bovis bacterium is passaged more than 100 times, wherein the M. bovis bacterium is selected from the group consisting of:
- the attenuated M. bovis bacteria strains deposited with the ATCC under accession numbers PTA-8694, PTA-8695, or PTA-8696;
- and one or more further immunologically active component(s) effective for the treatment of infections caused by a further cattle relevant pathogen other than M. bovis.
An immunogenic composition for the prophylaxis of cattle against microbiological infections, wherein said immunogenic composition comprises:
- a) one or more attenuated avirulent Mycoplasma bovis (M. bovis) antigens, wherein the M. bovis bacterium is passaged more than 100 times, wherein the M. bovis bacterium is selected from the group consisting of:
- the attenuated M. bovis bacteria strains deposited with the ATCC under accession numbers PTA-8694, PTA-8695, or PTA-8696;
- and
- b) one or more further immunologically active component(s) effective for the prophylaxis of microbiological infection in cattle caused by a cattle pathogen other than M. bovis.
A method of co-administration of two or more antigens to a cattle comprising, administering to said cattle one or more attenuated avirulent M. bovis antigen, wherein the M. bovis bacterium is passaged more than 100 times, wherein the M. bovis bacterium is selected from the group consisting of:
- the attenuated M. bovis bacteria strains deposited with the ATCC under accession numbers PTA-8694, PTA-8695, or PTA-8696;
- and one or more further immunologically active component(s) effective for the prophylaxis of infections caused by a further cattle relevant pathogen other than M. bovis.
Dependencies are inferred from the claim text.