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US 8,815,242 B2Granted
Avian derived antibodies
AssigneeSynageva BioPharma Corp.
InventorAlex J. Harvey
Life of this patent
Estimating the term…
Abstract
The invention is drawn to a composition comprising an isolated mixture of cytotoxic anti-CD20 antibody molecules produced in a transgenic avian. The antibody molecules have a heavy chain and a light chain whose amino acid sequences set forth in SEQ ID NOs: 4 and 5 and exhibit an increased level of cytotoxicity as compared to anti-CD20 antibody molecules produced in CHO cells.
Claims6
A composition comprising an isolated mixture of cytotoxic anti-CD20 antibody molecules produced in a transgenic avian, wherein the antibody molecules comprise a heavy chain and a light chain whose amino acid sequences set forth in SEQ ID NOs:
- 4 and 5, wherein the isolated mixture of cytotoxic anti-CD20 antibody molecules exhibit an increased level of cytotoxicity as compared to anti-CD20 antibody molecules produced in CHO cells and having the same amino acid sequence.
Dependencies are inferred from the claim text.