Graft prosthesis, materials and methods
AssigneesCook Biotech Incorporated, Cook Medical Technologies LLC
InventorsWilliam A. Cook, Michael C. Hiles, Thomas G. Kozma, Umesh H. Patel
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Abstract
A graft prostheses (11), materials and method for implanting, transplanting, replacing, or repairing a part of a patient. The graft prosthesis includes a purified, collagen-based matrix structure removed from a submucosa tissue source. The submucosa tissue source is purified by disinfection and removal steps to deactivate and remove contaminants, thereby making the purified structure biocompatible and suitable for grafting on and/or in a patient.
Claims20
A tissue matrix composition in the form of a powder, comprising:
- a tissue matrix material obtained from mammalian urinary tract tissue, the tissue matrix material in the form of a sterile powder and including submucosa and lamina propria from the urinary tract tissue, wherein the tissue matrix material retains one or more native growth factors from the urinary tract tissue including Fibroblast Growth Factor-2.
A tissue matrix composition in the form of a powder, comprising:
- a tissue matrix material obtained from mammalian urinary tract tissue, the tissue matrix material in the form of a sterile powder and including submucosa and lamina propria from the urinary tract tissue, wherein the tissue matrix material retains a proteoglycan, a growth factor, a glycoprotein, and a glycosaminoglycan.
Dependencies are inferred from the claim text.