Methods and apparatus for multi-vessel renal neuromodulation
AssigneeMedtronic Ardian Luxembourg S.a.r.l.
InventorDenise Zarins
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Abstract
Methods and apparatus are provided for multi-vessel neuromodulation, e.g., via a pulsed electric field. Such multi-vessel neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, the multi-vessel neuromodulation is applied to neural fibers that contribute to renal function. Such multi-vessel neuromodulation optionally may be performed bilaterally.
Claims8
A method for performing renal denervation, the method comprising:
- positioning a catheter within a renal artery of a human patient and proximate to renal nerves of the patient;
- intravascularly positioning a first electrode carried by the catheter within a first vessel branching from the renal artery;
- intravascularly positioning a second electrode carried by the catheter within a second vessel branching from the renal artery, wherein the second vessel is different than the first vessel;
- and
- thermally modulating a function of the renal nerves via radio frequency (RF) energy from the first and second electrodes.
Dependencies are inferred from the claim text.