Back to results
US 8,805,491 B2Granted
Microperfusive electrical stimulation
AssigneeZOLL Medical Corporation
InventorGary A. Freeman
Life of this patent
Estimating the term…
Abstract
A method of treating a patient in cardiac arrest (e.g., in fibrillation, electrochemical dissociation, or asystole), the method comprising delivering an agent for enhancement of cardiac function to the coronary arteries of the patient; and microperfusing the patient's cardiac tissue by electromagnetically stimulating the cardiac tissue at an energy level below a threshold sufficient to defibrillate the heart.
Claims10
A method of treating a patient in cardiac arrest (including in fibrillation, electrochemical dissociation, or asystole), the method comprising:
- delivering an agent for enhancement of cardiac function to the patient's coronary arteries, wherein delivering the agent comprises intravenous infusion of the agent and a circulatory enhancement method for delivery of the agent to the coronary arteries;
- and
- microperfusing the patient's cardiac tissue by electromagnetically stimulating the cardiac tissue with a plurality of microperfusing pulses, applied via electrodes external to the patient, wherein the microperfusing pulses are
- at an energy below a threshold sufficient to defibrillate the patient's heart and below a threshold sufficient to pace the patient's heart with hemodynamic output,
- but of a frequency, duration, and energy level to produce sufficient myocardial cell contraction for pumping of Calcium ions into the cell interior without causing electroporation of the myocardial cells.
2 more elements
Dependencies are inferred from the claim text.