Device for the analysis of an endocardiac signal of acceleration

A method comprising:

• collecting an endocardial acceleration (EA) signal over a plurality of cardiac cycles using an endocardial acceleration sensor of an implantable medical device;
• dividing the EA signal into a plurality of EA sub-signals, wherein each of the plurality of EA sub-signals corresponds to a single cardiac cycle of the plurality of cardiac cycles;
• identifying, in each of the plurality of EA sub-signals, at least one signal component associated with a type of heart sound, wherein each signal component is associated with the cardiac cycle of its EA sub-signal;
• extracting a characteristic of the at least one signal component for two or more of the plurality of cycles;
• calculating a correlation coefficient correlating the characteristic of the at least one signal component for a first cycle of the plurality of cycles to the characteristic of the at least one signal component for a second cycle of the plurality of cycles;
• and
• performing temporal retiming of the at least one signal component based on the calculated correlation coefficient to generate one or more adjusted signal components of the associated one or more EA sub-signals.

A non-transitory machine-readable storage medium having instructions stored thereon that, when executed by a processor, cause the processor to perform operations comprising:

• collecting an endocardial acceleration (EA) signal over a plurality of cardiac cycles using an endocardial acceleration sensor of an implantable medical device;
• dividing the EA signal into a plurality of EA sub-signals, wherein each of the plurality of EA sub-signals corresponds to a single cardiac cycle of the plurality of cardiac cycles;
• identifying, in each of the plurality of EA sub-signals, at least one signal component associated with a type of heart sound, wherein each signal component is associated with the cardiac cycle of its EA sub-signal;
• extracting a characteristic of the at least one signal component for two or more of the plurality of cycles;
• calculating a correlation coefficient correlating the characteristic of the at least one signal component for a first cycle of the plurality of cycles to the characteristic of the at least one signal component for a second cycle of the plurality of cycles;
• and
• performing temporal retiming of the at least one signal component based on the calculated correlation coefficient to generate one or more adjusted signal components of the associated one or more EA sub-signals.