Systems and methods for transfer of ions for analysis
AssigneePurdue Research Foundation
InventorsZheng Ouyang, Robert Graham Cooks, Sandilya Venkata Garimella, Jason David Harper, Nicholas Alan Charipar
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Abstract
The invention generally relates to systems and methods for transferring ions for analysis. In certain embodiments, the invention provides a system for analyzing a sample including an ionizing source for converting molecules of a sample into gas phase ions in a region at about atmospheric pressure, an ion analysis device, and an ion transfer member operably coupled to a gas flow generating device, in which the gas flow generating device produces a laminar gas flow that transfers the gas phase ions through the ion transfer member to an inlet of the ion analysis device.
Claims21
A system for analyzing a sample, the system comprising:
- a sample stage configured to hold a sample;
- an ionizing source arranged such that a distal tip of the ionizing source is pointed at the sample stage, wherein the ionizing source emits a discharge onto the sample stage that is capable of desorbing a portion of the sample from the sample stage and generating gas phase ions from the desorbed portion of the sample;
- an ion analysis device;
- and
- an ion transfer member operably coupled to a gas flow generating device, wherein the gas flow generating device produces a laminar gas flow that focuses and transfers the gas phase ions through the ion transfer member to an inlet of the ion analysis device.
A system for analyzing a sample, the system comprising:
- a sample stage configured to hold a sample;
- an ionizing source arranged such that a distal tip of the ionizing source is pointed at the sample stage, wherein the ionizing source emits a discharge onto the sample stage that is capable of desorbing a portion of the sample from the sample stage and generating gas phase ions from the desorbed portion of the sample;
- an ion analysis device;
- and
- an ion transfer member operably coupled to a gas flow generating device, wherein the gas flow generating device produces a laminar gas flow without recirculation regions that focuses and transfers the gas phase ions through the ion transfer member to an inlet of the ion analysis device.
Dependencies are inferred from the claim text.