Polyunsaturated fatty acid elongase
AssigneeBen-Gurion University of the Negev Research and Development Authority
InventorsZvi Hacohen, Inna Khozin Goldberg, Rivka Ofir, Iskandarov Umidjon
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Abstract
An isolated protein which is at least partially encoded by a polynucleotide sequence encoding a novel elongase is provided together with a composition which includes the isolated protein. A transgenic plant or a transgenic seed transformed by a polynucleotide encoding a protein which is at least partially encoded by a novel elongase is also provided. The invention also includes a process for making a very long-chain polyunsaturated fatty acid in a transformed cell or plant expressing the isolated protein which is at least partially encoded by a polynucleotide sequence encoding a novel elongase.
Claims20
A composition comprising an isolated protein having the amino acid sequence set forth in SEQ ID NO:
- 1 and a synthetic carrier.
A composition comprising an isolated protein having the amino acid sequence set forth in SEQ ID NO:
- 1, wherein said composition is an infant formula.
An isolated complementary DNA (cDNA) molecule encoding the protein of SEQ ID NO:
- 1.
An isolated polynucleotide comprising the nucleic acid sequence set forth in SEQ ID NO:
- 2.
An expression vector comprising a polynucleotide encoding the protein of SEQ ID NO:
- 1 and further comprising a heterologous regulatory element.
A transgenic plant or a transgenic seed transformed by a polynucleotide encoding the protein of SEQ ID NO:
- 1.
A transgenic seed, produced by a transgenic plant transformed by a polynucleotide encoding the protein of SEQ ID NO:
- 1.
A method of producing very long-chain polyunsaturated fatty acid (VLC-PUFA) in a plant or a plant cell, comprising the step of transforming a plant or a plant cell with a polynucleotide encoding the protein of SEQ ID NO:
- 1, thereby producing a VLC-PUFA in a plant or a plant cell.
A method of enhancing oil storage, arachidonic acid accumulation, or a combination thereof in a plant cell, comprising the step of transforming said plant cell with a polynucleotide encoding the protein of SEQ ID NO:
- 1, thereby enhancing oil storage, arachidonic acid accumulation, or a combination thereof in a plant cell.
Dependencies are inferred from the claim text.