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US 8,802,854 B2Granted
Crystalline forms of Prasugrel salts
AssigneeTeva Pharmaceutical Industries Ltd.
InventorsMihaela Tuksar, Tomislav Biljan, Miroslav Zegarac
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Abstract
Salts of prasugrel were prepared including, for example, crystalline forms of prasugrel hydrobromide. These salts are useful, for example, in medicaments that inhibit the aggregation of platelets.
Claims10
A crystalline Form I of Prasugrel hydrobromide according to formula I,
- characterized by:
- an X-ray powder diffraction pattern having peaks at 7.8, 14.4, 16.9, 22.0 and 25.1 degrees two theta±0.2 degrees two theta;
- a solid-state 13C NMR spectrum having peaks at 7.1, 11.2, 63.6, 123.7 and 203.4±0.2 ppm;
- or a combination thereof.
1 more element
A crystalline Form IA of Prasugrel hydrobromide according to formula I,
- characterized by an X-ray powder diffraction pattern having peaks at 7.9, 8.1, 13.5, 14.6 and 25.2 degrees two theta±0.2 degrees two theta.
Dependencies are inferred from the claim text.