US 8,802,850 B2Granted

Cyclopropyl modulators of P2Y12 receptor

AssigneeAuspex Pharmaceuticals, Inc.

InventorsTadimeti Rao, Chengzhi Zhang

Life of this patent

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Abstract

The present invention relates to new cyclopropyl modulators of P2Y12 receptor activity, pharmaceutical compositions thereof, and methods of use thereof.

Claims5

Dependent claims

A compound having the structural formula:

wherein each position represented as D has deuterium enrichment of no less than about 10%.

Dependencies are inferred from the claim text.

Facts

Application: 12/844,017Filed 27 Jul 2010 · us provisional application
Priority: 27 Jul 2009
Published: US 2012/0301458 A129 Nov 2012
Granted: 12 Aug 2014
Term ends: Not estimatedThe source records don’t support an estimate.

Classification17 codes

C07D 487/04
In which the condensed system contains two hetero rings: ortho-condensed systems
A61K 31/519
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim: ortho- or peri-condensed with heterocyclic rings
A61K 45/06
Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00: mixtures of active ingredients without…
A61P 3/14
For electrolyte homeostasis: for calcium homeostasis

Family

Application61/228,913Us provisional application · filed 27 Jul 2009
US 2012/0301458 A1Pre-grant publication · published 29 Nov 2012
US 8,802,850 B2This patent

From the US filing history. Foreign family members aren’t listed.

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