Method of treating or preventing pain
AssigneeNovaremed Limited
InventorEliahu Kaplan
Life of this patent
Estimating the term…
Abstract
Compounds for use in the treatment or prophylaxis of pain, including acute and chronic pain (e.g., nociceptive pain, neuropathic pain, headaches, migraine), represented by general formula I: in which: the dotted line represents a single or a double bond; and R5 and R5′ are independently —H, —OH or —OR6, where R6 is a linear or branched C1-C4 alkyl; X is —CH2O—; Z is —CH2CH2O—, —CH(CH3)CH2O— or —CH2CH(CH3)O—; m is 1; and n is an integer of 1-5. The compounds of the invention are also effective for reducing inflammation and may be used alone or in combination with other analgesics.
Claims20
A method for treating nociceptive pain selected from somatic, visceral, and myofascial or edema in a human or non-human animal patient in need thereof, which method comprises administering to said patient a therapeutically effective amount of at least one compound represented by formula I:
- wherein:
- represents a single or a double bond;
- R5 and R5′ are independently —H, —OH or —OR6, wherein R6 is a linear or branched C1-C4 alkyl;
- X is —CH2O—;
- Z is —CH2CH2O—, —CH(CH3)CH2O— or —CH2CH(CH3)O—;
- m is 1;
- and
- n is an integer of 1, 2, 3, 4, or 5;
- or a pharmaceutically acceptable salt, prodrug, metabolite, or hydrate thereof.
A method for treating somatic pain, visceral pain, myofascial pain, or edema in a human patient in need thereof, which method comprises administering to said patient a therapeutically effective amount of the compound:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.